So I run hills - the steeper the better. Alas, there are only a handful of hills that I know of
Can't help you on the route suggestion, but I'll second the 'I run hills' sentiment. Most people with bum knees hate hills. My 40 year old knees are starting to back-talk me more. Are you able to open up pretty good on the downhill?
BTW: This race, www.bluescruiseultra.com
if you like long ones, has an awsome mix of hills. About 3 hours from gunks.